Varicose Vein Treatment

Some patients receiving Varithena® (polidocanol injectable foam) only need a single treatment.
Additional treatment may be needed, depending on the number and size of veins to be treated.

During treatment

  • Treatment with Varithena is minimally invasive and nonsurgical (no incisions required)
  • The doctor usually numbs the injection site, but no additional anesthesia is required
  • The doctor administers a small amount of Varithena through a catheter or by direct injection into the malfunctioning vein
  • It usually takes the doctor less than an hour to administer Varithena
  • Following administration, the doctor applies bandages and compression stockings to the leg 

After treatment

Patients may resume some activities the same day as treatment.
Heavy exercise should be avoided for one week.
Post-treatment bandages need to be kept dry and in place for 48 hours, and compression stockings must be worn on the treated leg for 2 weeks.
For a month, patients should walk at least 10 minutes a day and avoid long periods of inactivity.
If you have received treatment with Varithena, your doctor will give you additional instructions for post-treatment self care.

Self-care schedule for patients after treatment with Varithena


Is Varithena® right for you?
Start the discussion with your doctor today.

About insurance coverage
Insurance carriers may cover varicose vein treatment.
Coverage may depend on the
severity of the varicose veins
and symptoms. If you have
questions about your coverage,
your doctor's office
may be able to assist you.

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You are encouraged to report negative side effects of prescription drugs to the FDA. Visit, or call 1-800-FDA-1088.


Varithena® (polidocanol injectable foam) is a prescription medicine used to treat varicose veins caused by problems with the great saphenous vein (GSV) and other related veins in the leg's GSV system. Varithena® improves symptoms related to or caused by varicose veins, and the appearance of varicose veins.


You should not be treated with Varithena® if you are allergic to polidocanol or have clots in your blood vessels.

Severe allergic reactions have been reported in people treated with liquid forms of polidocanol and some patients have died from these reactions. Varithena® is a foam made from polidocanol. A healthcare professional will observe you for signs of allergic reactions for at least 10 minutes after you are treated with Varithena®.

Tell your doctor about all your medical conditions, including if you have:

  • Arterial disease (a disease of the blood vessels)
  • Reduced mobility
  • A history of blood clots in the veins or lungs
  • Had major surgery in the past 3 months
  • Recently had a long hospital stay
  • Become pregnant or were recently pregnant

The most common side effects seen with Varithena® are leg pain or discomfort, injection site bruising or pain, and potentially serious blood clots in the leg veins. These are not all the possible side effects of Varithena®. Tell your healthcare provider about any side effect that bothers you or that does not go away. You can also report side effects to the FDA at 1-800-FDA-1088. Varithena® is administered by your doctor. Doctors using Varithena® must be experienced in vein procedures and trained in using Varithena®.

See Full Prescribing Information for Varithena®.

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