Bulging Veins in Legs

Varicose veins are enlarged, bulging veins that most often occur in the leg's great saphenous vein (GSV) system. Varicose veins are usually visible and can cause uncomfortable symptoms such as swelling and achiness.
Varithena® (polidocanol injectable foam) treats varicose veins caused by problems with the GSV system. Varithena® does not treat all forms of varicose veins. Please talk with your doctor to see if Varithena® is right for you.                                         

How varicose veins form

Varicose veins occur when the tiny valves inside the veins become weaker, causing blood to back up and make the veins swell.

Why varicose veins form

Tiny valves help the
leg veins work against
gravity to push blood
back to the heart.
But if valves weaken,
blood can leak backwards
and pool, relting in
varicose veins.

Common symptoms

Varicose veins can cause uncomfortable symptoms, such as heaviness, achiness, swelling, throbbing, and itching. Varicose veins often bulge above the surface of the skin, but they are not always visible.

Common risk factors

Family history, aging, being overweight or obese, and working at jobs requiring prolonged standing can increase the risk for varicose veins.

About insurance coverage

Insurance carriers may cover varicose vein treatment. Coverage may depend on the severity of the varicose veins and symptoms. If you have questions about your coverage, your doctor's office may be able to assist you.

Is Varithena™ right for you? Start the discussion with your doctor today.

Varicose veins occur most often in the leg's GSV system.

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You are encouraged to report negative side effects of prescription drugs to the FDA. Visit www.fda.gov/medwatch, or call 1-800-FDA-1088.


Varithena® (polidocanol injectable foam) is a prescription medicine used to treat varicose veins caused by problems with the great saphenous vein (GSV) and other related veins in the leg's GSV system. Varithena® improves symptoms related to or caused by varicose veins, and the appearance of varicose veins.


You should not be treated with Varithena® if you are allergic to polidocanol or have clots in your blood vessels.

Severe allergic reactions have been reported in people treated with liquid forms of polidocanol and some patients have died from these reactions. Varithena® is a foam made from polidocanol. A healthcare professional will observe you for signs of allergic reactions for at least 10 minutes after you are treated with Varithena®.

Tell your doctor about all of your medical conditions, including if you

  • have arterial disease (a disease of the blood vessels)
  • have reduced mobility
  • have a history of blood clots in the veins or lungs
  • have had major surgery in the past 3 months
  • have recently had a long hospital stay
  • are pregnant or have recently been pregnant

The most common side effects seen with Varithena® are leg pain or discomfort, injection site bruising or pain, and potentially serious blood clots in the leg veins. These are not all of the possible side effects of Varithena®. Tell your healthcare provider about any side effect that bothers you or that does not go away. You can also report side effects to the FDA at 1-800-FDA-1088. Varithena® is administered by your doctor. Doctors using Varithena® must be experienced in vein procedures and trained in using Varithena®.

See Full Prescribing Information for Varithena®.

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