DC Bead™ Clinical Bibliography

September 2006 – December 2018
25 Publications
782 Patients*

Drug-Eluting Bead: DEBIRI™

DC Bead™ with irinotecan for the local treatment of liver metastases from colorectal cancer

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*Important note regarding patient numbers. Please note that patient numbers in red were not counted toward the total number of patients given above. Patient numbers in green reflect the numbers counted in the total, which were potentially duplicated by the numbers in red. Numbers in black were not considered to have potential duplications and were included in the total number above.
Publication title: Irinotecan-Eluting 75–150-μm Embolics Lobar Chemoembolization in Patients with Colorectal Cancer Liver Metastases: A Prospective Single-Center Phase I Study
Authors Fereydooni A., Letzen B., Ghani M.A
Journal J Vasc Interv Radiol
Patients 14
Date published December 2018
Impact factor 2.758
Publication title: PARAGON II – A single arm multicenter phase II study of neoadjuvant therapy using irinotecan bead in patients with resectable liver metastases from colorectal cancer
Authors Jones RP, Malik HZ, Fenwick SW, et al
Journal Eur J Surg Oncol
Patients 40
Date published December 2016
Impact factor Unknown
Publication title: Early experience with 70-150 μm irinotecan drug-eluting beads (M1-DEBIRI) for the treatment of unresectable hepatic colorectal metastases
Authors Akinwande O, Scoggins C, Martin RC
Journal Anticancer Res
Patients 15
Date published July 2016
Impact factor 1.865
Publication title: Small versus large-sized drug-eluting beads (DEBIRI) for the treatment of hepatic colorectal metastases: a propensity score matching analysis
Authors Akinwande OK, Philips P, Duras P, et al
Journal Cardiovasc Intervent Radiol
Patients 226
Date published April 2015
Impact factor 2.210
Publication title: Real-life report on chemoembolization using DEBIRI for liver metastases from colorectal cancer
Authors Stutz M, Mamo A, Valenti D, et al
Journal Gastroenterol Res Pract
Patients 27
Date published February 2015
Impact factor 1.859
Publication title: Radiological assessment of response to neoadjuvant transcatheter hepatic therapy with irinotecan-eluting beads (DEBIRI®) for colorectal liver metastases does not predict tumour destruction or long-term outcome
Authors Jones RP, Stättner S, Dunne DFJ, et al
Journal Eur J Surg Oncol
Patients 22
Date published October 2013
Impact factor Unknown
Publication title: Hepatic activation of irinotecan predicts tumour response in patients with colorectal liver metastases treated with DEBIRI: Exploratory findings from a phase II study
Authors Jones RP, Sutton P Greensmith RMD, et al
Journal Cancer Chemotherapy and Pharmacology
Patients 10 (patients not counted due to potential duplication with Jones et al EJSO 2013)
Date published August 2013
Impact factor Unknown
Publication title: Transarterial chemoembolization using DEBIRI for treatment of hepatic metastases from colorectal cancer
Authors Narayanan G, Barbery K, Suthar R, et al
Journal Anticancer Res
Patients 28
Date published May 2013
Impact factor 1.865
 
Publication title: First human study in treatment of unresectable liver metastases from colorectal cancer with irinotecan-loaded beads (DEBIRI)
Authors Eichler K, Zangos S, Mack M
Journal Int J Oncol
Patients 11
Date published October 2012
Impact factor Unknown
 
Publication title: Intra-arterial infusion of irinotecan-loaded drug-eluting beads (DEBIRI) versus intravenous therapy (FOLFIRI) for hepatic metastases from colorectal cancer: Final results of a phase III study
Authors Fiorentini G, Aliberti C, Tilli M, et al
Journal Anticancer Res
Patients 36 (26 counted due to overlap of 10 patients with Aliberti et al. Anticancer Research 2011)
Date published April 2012
Impact factor 1.865
Publication title: Hepatic arterial chemoembolization adopting DC Bead drug eluting bead loaded with irinotecan (DEBIRI) versus systemic therapy for hepatic metastases from colorectal cancer: A randomized study of efficacy and quality of life
Authors Fiorentini G, Aliberti C, Benea G, et al
Journal Ann Gastroenterol Hepatol
Patients 36 (patient number not counted due to duplication with Fiorentini et al. Anticancer Res 2012)
Date published March 2012
Impact factor Unknown
Publication title: Trans-arterial chemoembolization of metastatic colorectal carcinoma to the liver adopting DC Bead®, drug- eluting bead loaded with irinotecan: Results of a phase II clinical study
Authors Aliberti C, Fiorentini G, Muzzio PC, et al
Journal Anticancer Res
Patients 82
Date published December 2011
Impact factor 1.865
 
Publication title: Hepatic intra-arterial injection of drug-eluting bead, irinotecan (DEBIRI) in unresectable colorectal liver metastases refractory to systemic chemotherapy: Results of multi-institutional study
Authors Martin RC, Joshi J, Robbins K, et al
Journal Ann Surg Oncol
Patients 55 (These patients not counted due to potential duplication with Martin et al. CVIR 2010)
Date published January 2011
Impact factor 3.857
Publication title: Unenhanced and contrast-enhanced ultrasonography during hepatic transarterial embolization and chemoembolization with drug-eluting beads
Authors Moschouris H, Malagari K, Kornezos I, et al
Journal Cardiovasc Intervent Radiol
Patients 16 tumours (Number of patients not specified)
Date published December 2010
Impact factor 2.210
Publication title: Toxicity of irinotecan-eluting beads in the treatment of hepatic malignancies: Results of a multi-institutional registry
Authors Martin RC, Howard J, Tomalty D, et al
Journal Cardiovasc Intervent Radiol
Patients 109 (84 mCRC patients counted)
Date published October 2010
Impact factor 2.210
Publication title: Surgical downstaging and neo-adjuvant therapy in metastatic colorectal carcinoma with irinotecan drug- eluting beads: A multi-institutional study
Authors Bower M, Metzger T, Robbins K, et al
Journal HPB (Oxford)
Patients 55 (These patients not counted due to potential duplication with Martin et al. CVIR 2010)
Date published February 2010
Impact factor 3.131
Publication title: Transarterial chemoembolisation (TACE) using irinotecan-loaded beads for the treatment of unresectable metastases to the liver in patients with colorectal cancer: An interim report
Authors Martin RC, Robbins K, Tomalty D, et al
Journal World J Surg Oncol
Patients 55 (These patients not counted due to potential duplication with Martin et al. CVIR 2010)
Date published November 2009
Impact factor 1.792
Publication title: Transarterial chemoembolization of metastatic colorectal carcinoma with drug-eluting beads, irinotecan (DEBIRI): Multi-institutional registry
Authors Martin RC, Joshi J, Robbins K, et al
Journal J Oncol
Patients 30 (These patients not counted due to potential duplication with Martin et al. CVIR 2010)
Date published October 2009
Impact factor 4.528
Publication title: TACE of liver metastases from colorectal cancer adopting irinotecan-eluting beads: Beneficial effect of palliative intra-arterial lidocaine and post-procedure supportive therapy on the control of side effects
Authors Fiorentini G, Aliberti C, Benea G, et al
Journal Hepatogastroenterology
Patients 20 (These patients not counted due to potential duplication with Aliberti et al. Anticancer Research 2011)
Date published November 2008
Impact factor Unknown
Publication title: Intraarterialhepatic chemoembolization of liver metastases from colorectal cancer adopting irinotecan- eluting beads: Results of a phase II clinical study
Authors Fiorentini G, Aliberti C, Turrisi G, et al
Journal In Vivo
Patients 20 (These patients not counted due to potential duplication with Aliberti et al. Anticancer Research 2011)
Date published November 2007
Impact factor 4.556
Publication title: Trans-arterial chemoembolization (TACE) of liver metastases from colorectal cancer using irinotecan-eluting beads: Preliminary results
Authors Aliberti C, Tilli M, Benea G, et al
Journal Anticancer Res
Patients 10 (These patients not counted due to potential duplication with Aliberti et al. Anticancer Research 2011)
Date published September 2006
Impact factor 1.865

Combination Therapy with DEBIRI™

Publication title: Trans-arterial chemoembolization with irinotecan-loaded drug-eluting beads (DEBIRI) and capecitabine in refractory liver prevalent colorectal metastases: a phase II single-centre study
Authors Iezzi R, Marsico VA, Guerra A, et al
Journal Cardiovasc Intervent Radiol
Patients 20
Date published March 2015
Impact factor 2.210
Publication title: Concomitant capecitabine with hepatic delivery of drug eluting beads in metastatic colorectal cancer
Authors Akinwande OK, Miller A, Hayes D, et al
Journal Anticancer Res
Patients 171
Date published December 2014
Impact factor 1.865
Publication title: Fluorouracil, leucovorin and irinotecan combined with intra-arterial hepatic infusion of drug-eluting beads preloaded with irinotecan in unresectable colorectal liver metastases: Side effects and results of a concomitant treatment schedule. Clinical investigation
Authors Kekez D, Badzek S, Prejac J, et al
Journal Tumori
Patients 7
Date published September 2014
Impact factor 1.304
Publication title: Irinotecan drug-eluting beads in the treatment of chemo-naive unresectable colorectal liver metastasis with concomitant systemic fluorouracil and oxaliplatin: Results of pharmacokinetics and phase I trial
Authors Martin RC 2nd, Scoggins CR, Tomalty D, et al
Journal J Gastrointest Surg
Patients 10
Date published August 2012
Impact factor 2.813

The literature references provided in this bibliography were evaluated for safety and performance, as well as state of the art application. Case reports are included if a specific safety issue was reported. Literature reporting the concomitant use of doxorubicin loaded DC Bead™ with other therapies appear in the Combination Therapy section.

Note regarding the impact factor of each journal: The impact factors were obtained from the Research Gate website on 05-December-2018, https://www.researchgate.net/publication/326016068_2018_Journal_Impact_Factor_2018/download. The downloaded pdf was entitled: “2018JournalImpactFactor.” Impact factors noted as ‘unknown’ were not found in the 2018 Journal Impact Factor document.

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