The material is called nitinol. It has already been extensively tested for long-term use inside the body and is used and well-tolerated in respiratory medicine, interventional radiology and angioplasty (e.g., stents.) Nitinol is an alloy of nickel and titanium.1  Coils should not be used in patients with hypersensitivity or allergy to nitinol or its constituent metals.

Since 2008, Coils have been the subject of clinical trials. They are commercially available since 2010.

More than 7.000 Coil treatments have been performed.


This treatment has been the subject of many investigations and clinical studies and showed safety and improvements to quality of life, lung function, and exercise capacity.2-7

The minimally-invasive procedure is performed bilaterally (on both the left and right lungs) and takes approximately 35 to 45 minutes per treatment. The second lung should be treated 1 – 3 months after the first procedure.

Coils are intended as permanent implants. While it is possible to remove single Coils, they should be removed only if medically indicated.

An MRI scan can be performed after Coil treatment provided that specific settings are used. Your Patient Implant Card provides further information on this.

Please share these details with your doctor before having an MRI scan.

1Barras CDJ, Myers KA. Nitinol – its use in vascular surgery and other applications. Eur J Vasc Endovasc Surg. 2000 Jun;1(6):564-9.
2 Klooster K, Ten Hacken NHT, Franz I, et al. Lung Volume Reduction Coil Treatment in Chronic Obstructive Pulmonary Disease Patients with Homogeneous Emphysema: A Prospective Feasibility Trial. Respiration 2014; DOI: 10.1159/000362522
3Deslée G, Mal H, Marquette CH,et al. Lung Volume Reduction Coil Treatment vs Usual Care in Patients With Severe Emphysema. The REVOLENS Randomized Clinical Trial, JAMA. 2016; DOI:10.1001/jama.2015.17821
4Shah PL, Zoumot Z, Singh S, et al. Endobronchial coils for the treatment of severe emphysema with hyperinflation (RESET): A randomised controlled trial. Lancet Respir Med 2013; DOI: 10.1016/S2213-2600(13)70047-X
5Slebos DJ, et al. Bronchoscopic Coil Treatment for Patients with Severe Emphysema: A Meta-Analysis. Respiration 2015; DOI: 10.1159/000431384
6Hartman JE, et al. Long-term follow-up after bronchoscopic lung volume reduction treatment with coils in patients with severe emphysema. Respirology 2014; DOI: 10.1111/resp.12435
7Sciurba FC, Criner GJ, Strange C, et al. Effect of endobronchial coils vs usual care on exercise tolerance in patients with severe emphysema: The RENEW Randomized Clinical Trial. JAMA 2016 ; DOI:10.1001/ jama.2016.6261.